
Understanding dynamic cell-matrix communications in health and diseases
The extracellular matrix (ECM) is not merely a structural scaffold but a dynamic environment that regulates cell proliferation, differentiation, and migration. Our team studies how proteinases and endocytosis control cell–ECM communication to maintain tissue homeostasis and how its disruption contributes to disease.
Welcome to our laboratory!
東京農工大学 農学部附属 硬蛋白質利用研究施設 応用蛋白質化学研究室 准教授 山本和博

Associate Professor at Tokyo University of Agriculture and Technology Honorary Lecturer at University of Liverpool
2022 MAY – present: Arthritis UK Bridging Fellow, Institute of Life Course and Medical Sciences, University of Liverpool.
2022 JAN – 2025 FEB: Lecturer, Institute of Life Course and Medical Sciences, University of Liverpool.
2019 JAN – 2022 JAN: Tenure Track Fellow, Institute of Life Course and Medical Sciences, University of Liverpool.
2017 JUN – 2022 SEP: Versus Arthritis Career Development Fellow, Institute of Life Course and Medical Sciences, University of Liverpool.
2014 FEB – 2017 JUN: Arthritis Research UK Research Fellow, Kennedy Institute of Rheumatology, University of Oxford.
2011 JUL – 2014 JAN: Postdoctoral Research Associate, Kennedy Institute of Rheumatology, University of Oxford.
2008 DEC – 2011 JUL: Postdoctoral Research Associate, Kennedy Institute of Rheumatology, Imperial College London.
2006 APR – 2008 DEC: Postdoctoral Research Fellow, Kihara Institute for Biological Research, Yokohama City University, Japan.
Interested in joining our lab? Please see the information here!

NEWS
・Excited to see our paper out on 17th May: Proteomic signatures of equine dental tooth tissues in ageing and disease! Great study, and likely the last paper with Liverpool as my sole affiliation.
・In early May, Kazu’s first Japanese commentary since returning to Japan has been republished in two additional monthly publications: The Cell (Vol. 58, No. 5) and Allergy & Rheumatic Diseases (Vol. 46, No. 625).
・On 1st May, after plenty of rain, the sunshine finally returned and welcomed us. We enjoyed a lovely BBQ together with Shinji Miyata’s lab and the labs of Yohei Yamagata and Mizuki Tanaka. A big thanks goes to my B4s for making this happen! Apologies, we were having too much fun to take any photos…
・On 30th April , Kazu Ooi (Kanazawa University) visited us and delivered an inspiring seminar that our students thoroughly enjoyed. We look forward to further developing our long-standing collaboration on temporomandibular joint osteoarthritis!
・In April, several new members joined our team. Join me in welcoming Ryo Muko, Yuna Sekido, Naoya Shara, Baldorj Nomin, Kiri Nakamura, and Kaho Ueyama! We’re excited to have you on board and look forward to working together and seeing you grow&shine!!!
・On 6th March, Kazu was awarded the JSPS Bilateral Joint Research Project grant in collaboration with the Royal Society (UK). This 2 year’s initiative connects TUAT with the University of Manchester and the University of Liverpool. We are excited to further strengthen our collaboration with Dr. Joan Chang, Dr. David Wilkinson, and their students!
NEWS archive
Get In Touch
- Kazuhiro-Yamamoto@go.tuat.ac.jp
- TUAT homepage http://www.collagen-institute.jp/index.html
- Kazuhiro.yamamoto@liverpool.ac.uk
- Liverpool homepage https://www.liverpool.ac.uk/people/kazuhiro-yamamoto/professional#tabbed-content
- (042) 367 5789
- LinkedIn https://www.linkedin.com/in/kazuhiro-yamamoto-677763137/
Drop By
〒183-8509
東京都府中市幸町3-5-8
東京農工大学農学部附属硬蛋白質利用研究施設
Scleroprotein and Leather Institute, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwaicho, Fuchu, Tokyo 183-8509, Japan

















